Extra-abdominal desmoid tumor fibromatosis: a multicenter EMSOS study

نویسندگان

چکیده

Abstract Background Extra-abdominal desmoid tumor fibromatosis (DTF) is a rare, locally aggressive soft tissue tumour. The best treatment modality for this patient cohort still object of debate. Questions/purpose This paper aimed to (1) compare the outcomes DTF after different modalities, (2) assess prognostic factors recurrence following surgical excision, and (3) progression during observation. Methods was retrospective multicenter study under patronage European Musculoskeletal Oncology Society (EMSOS). All seven centres involved were tertiary referral tumours. Baseline demographic data collected all patients as well on diagnosis, tumour characteristics, clinical features, modalities whether they had any predisposing DTF. Results Three hundred eighty-eight (240 female, 140 male) with mean age 37.6 (±18.8 SD, range: 3–85) included in study. Two fifty-seven (66%) underwent excision ADF, 70 (18%) observed without therapy, residual conservative treatments. There no significant differences terms or between groups. After younger age, recurrent disease larger size risk recurrence, while tumours around shoulder girdle painful lesions at observational group. Conclusion Local rate surgery similar rates Hence, observation seems be justified, considering case dimensional 2 consecutive controls (3 6 months) lesions, particular attention girdle.

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ژورنال

عنوان ژورنال: BMC Cancer

سال: 2021

ISSN: ['1471-2407']

DOI: https://doi.org/10.1186/s12885-021-08189-6